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方铭
宣布时候:2018-01-02   作者:  点击次数:

天空体育:

根基信息

方铭,男,博士生导师,闽江学者特聘传授(2017),当选福建省百万万人材工程打算,福建省高条理人材B类,当选第十批厦门市双百打算,福建水产学会理事。

Email: fangming618@126.com

通信地点:厦门阛阓美区印斗路43号,集美天空体育水产学院(361021




研讨乐趣

  1. 植物份子育种。开辟/操纵进步前辈的份子选育手艺针对大黄鱼等停止劣种选育。

  2. 植物经济性状遗传剖析。连系多组学及份子生物学手艺检测植物发展、抗病等经济性状联系关系的功效基因及因果突,病研讨因果渐变调控机制。

  3. 人类疾病遗传剖析。接纳多组学手艺检测人类疾病相干的功效基因及因果渐变,首要针对人类炎症性肠病(克伦恩病及溃疡性结肠炎)、银屑病、糖尿病、类风湿性枢纽炎、肺癌等疾病停止研讨。

掌管科研名目

1. 国度天然迷信基金面上名目,31672399,操纵高通量测序数据检测顺式感化遗传变异的新方式及其利用,2017/01-2020/1264万,在研,掌管

2. 国度天然迷信基金面上名目,31872560,基于混池测序手艺的黄姑鱼红头病抗病位点超邃密定位,2019/01-2022/12,在研,62万,掌管

3.国度重点研发打算“蓝色粮仓科技立异”重点专项子使命,基因组育种手艺平台构建和黄姑鱼性别相干性状阐发,2018/12-2021/12,在研,115万,掌管。

4. 集美天空体育科研预研名目,大黄鱼高不饱和脂肪酸(HUFA)的遗传剖析,2019.7-2022.7,200万,掌管。

5. 国度天然迷信基金青年迷信基金名目,31001001,畜禽系谱群体主要经济性状位点的高效率邃密定位方式,2011/01-2013/1219万,已结题,掌管

6. 黑龙江省教导厅新世纪优异人材撑持打算,1253—NCET—001,畜禽全基因组育种值展望的高维阐发方式,2013/06-2017/0620万,结题,掌管

颁发论文( #配合作者; *通信作者)


  1. Dang jiang; Wanbo Li; Zhiyong Wang; * Ming Fang* Genome‑Wide Identifcation of Cis‑acting Expression QTLs in Large Yellow Croaker, Marine Biotechnology, 2021, http://doi.org/10.1007/s10126-020-10017-0.

  2. Wenjing Zhang; Wanbo Li; Guijia Liu; Linlin Gu; Kun Ye; Yongjie Zhang; Wei Li; Dan Jiang; Zhiyong Wang;* Ming Fang* Evaluation for the effect of low-coverage sequencing on genomic selection in large yellow croaker, Aquaculture, 2020, 534: 736323.

  3. Hailiang Huang#, Ming Fang#, Luke Jostins#, Masa U. Mirkov, International the IBD Genetics Consortium, Michel Georges, Jeffrey C. Barret and Mark J. Daly. Fine-mapping inflammatory bowel disease loci to single-variant resolution. 2017, Nature, 13;547(7662):173-178.

  4. Liu G , Han Z , Jiang D , Li W, Zhang WJ, Ye K, Gu LL, Dong LS, Fang M*, Wang ZY*. Genome-wide association study identifies loci for traits related to swim bladder in yellow drum (Nibea albiflora). Aquaculture, 2020, 526:735327.

  5. Liu G, Dong L, Gu LL, Han ZF, Zhang WJ, Fang M* & Wang ZY*. Evaluation of Genomic Selection for Seven Economic Traits in Yellow Drum (Nibea albiflora). Marine Biotechnology. 21, 806–812 (2019).

  6. Li Y, Li B, Yang M, Han H, Chen T, Wei Q, Miao Z, Yin L, Wang R, Shen J, Li X, Xu X, Fang M* and Zhao S* (2020) Genome-Wide Association Study and Fine Mapping Reveals Candidate Genes for Birth Weight of Yorkshire and Landrace Pigs. Frontier in Genetics. 11:183.

  7. Jiang, D., Xin, C., Ye, J. Fang M.*. ICGRM: integrative construction of genomic relationship matrix combining multiple genomic regions for big dataset. BMC Bioinformatics 20, 731 (2019)..

  8. Jun-Feng Gao, Yuan Gao, Jian-Hua Qiu, Qiao-cheng Chang, Yan Zhang, Ming Fang*, Chun-Ren Wang*. De novo assembly and functional annotations of the transcriptome of Metorchis orientalis (trematoda: Opisthorchiidae). 2018. Experimental Parasitology.

  9. Changliang Qiu#, Linsong Dong#, Shijun Xiao, Shuangbin Xu, Ming Fang, Zhiyong Wang. Genetic parameters estimation of Nine Quantitative Traits by a marker-based method in Large Yellow Croaker, Larimichthys crocea (Rechardson). 2017. Aquaculture Research.

  10. Yuxue Gao, Linsong Dong, shuangbin Xu, Shijun Xiao, Ming Fang, Zhiyong Wang*. Genome-wide association study using single SNP analysis and Bayesian method for swim bladder index and gonadosomatic index in large yellow croaker. 2017. Aquaculture.

  11. Linsong Dong; Ming Fang, Zhiyong Wang. Prediction of genomic breeding values using new computing strategies for the implementation of MixP. 2017. Scientific Reports.

  12. Jun-Feng Gao, Guo-Hua Liu, Hong Duan, Yuan Gao, Yan Zhang, Qiao-Cheng Chang, Ming Fang, Chun-Ren Wang. Complete mitochondrial genomes of Triodontophorus serratus and Triodontophorus nipponicus, and their comparison with Triodontophorus brevicauda.. 2017. Experimental Parasitology.

  13. Ming Fang, Michel Georges*, BayesFM: a software program to fine-map multiple causative variants in GWAS identified risk loci. 2016, Biorxiv

  14. Yang Deguang#, Han Shanshan#, Jiang Dan#, Yang Runqing and Ming Fang*. Inference of posterior inclusion probability of QTLs in Bayesian shrinkage analysis. Genet. Res. 2015. doi:10.1017/S001667231500001.

  15. Jiang Dan, Ma Guoda, Yang Runqing, Li Kesen *, and Ming Fang*. Bayesian model selection for multiple QTLs mapping combining linkage disequilibrium and linkage. Genet. Res. 2014. doi: 10.1017/S0016672314000135.

  16. Ming Fang*, Fu Weixuan, Zhang Qin*, Ding Xiangdong, Sun Dongxiao*. A Multiple-SNP Approach for Genome-Wide Association Study of Milk Production Traits in Chinese Holstein Cattle. PLOS ONE, 2014, 9(8):e99544.

  17. Dan Jiang, Yanli Wu, Jiahan li, Yang Wu, Ming Fang and Runqing Yang. Cox regression model for dissecting genetic architecture of survival time. Genomics, 2014, 104 (6):472-476.

  18. Xiaoping Wu#, Ming Fang#, Lin Liu, Sheng Wang, Jianfeng Liu, Xiangdong Ding, Shengli Zhang, Qin Zhang, Yuan Zhang, Lv Qiao, Mogens Sand Lund, Guosheng Su, Dongxiao Sun*. Genome wide association studies for body conformation traits in the Chinese Holstein cattle population. BMC Genomics, 2013, 14:897.

  19. Ming Fang*. A fast expectation-maximum algorithm for fine-scale QTL mapping. Theoretical and Applied Genetics, 2012,125:1727-1734.

  20. Ming Fang*, Dan Jiang, Dandan Li, Runqing Yang. Improved LASSO priors for shrinkage QTL mapping. Theoretical and Applied Genetics, 2012, 124(7):1315-24.

  21. Xiaojing Zhou, Ming Fang, Jiahan Li, Daniel R Prows, Runqing Yang. Characterization of genomic imprinting effects and patterns with parametric accelerated failure time model. Molecular Genetics and Genome, 2012, 287(1):67-7.

  22. Ming Fang#, Jianfeng Liu#, Qin Zhang* and Dongxiao Sun*. QTL Mapping in Outbred Half-sib Families Using Bayesian Model Selection. Heredity, 2011, 107, 265-276.

  23. Ming Fang*. Bayesian shrinkage mapping of quantitative trait loci in variance component models. BMC Genetics, 2010, 11(1):1-10.

  24. Ming Fang*, Shengcai Liu, Dan Jiang, Bayesian composite model space approach for mapping quantitative trait loci in variance component model. Behav Genet, 2009, 39: 337-346.

  25. Gao H, Ming Fang, Liu JF, Zhang Q*, Bayesian shrinkage mapping for multiple QTL in half-sib families. Heredity, 2009, 103(5): 368-376.

  26. Ming Fang*, Dan Jiang, Lijun Pu, Huijiang Gao, Peng Ji, Hongyi Wang, et al., Multitrait analysis of quantitative trait loci using Bayesian composite space approach. BMC Genetics, 2008, 9:48.

  27. Ming Fang*, Dan Jiang, Huijiang Gao, Dongxiao Sun, RQ Yang, Qin Zhang, A new Bayesian automatic model selection approach for mapping quantitative trait loci under variance component model. Genetica, 2008, 135(3): 429-439.

  28. Ming Fang*, Dan Jiang, Xu Chen, Lijun Pu, Shengcai Liu, Bayesian analysis of genetic architecture of quantitative trait using data of crosses of multiple inbred lines. Genetica, 2008, 134(3): 367-375.

  29. Runqing Yang*, Ming Fang, Mapping quantitative trait loci in line cross with repeat records. BMC Genetics, 2007, 8: 47.

 

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